Search results for " Down syndrome"

The cholinergic system in Down's syndrome

2006

The cholinergic system is one of the most important modulatory neurotransmitter systems in the brain. Alterations of the transmission communicators are accompanied by reduction of the cortical activity, which is associated with a learning and memory deficit. Down's syndrome is a pathological condition characterized by a high number of abnormalities that involve the brain.The cholinergic system is involved in alterations of the neurological system such as severe learning difficulties.To explain these alterations, important results are obtained from studies about murine trisomy 16 (animal model of Down's syndrome).The results obtained provide useful elements in the improvement of knowledge ab…

Gross motor proficiency and intellectual functioning

2018

This cross-sectional study examines differences in gross motor proficiency as a function of different intellectual functioning profiles. Two motor areas have been investigated as being equally essential to gross motor functions in every-day life: locomotion and object control. It aims to compare gross motor skills endorsed by children with Down syndrome (DS), children with borderline intellectual functioning (BIF), and typically developing children (TDC). Group 1 was composed of 18 children with DS (chronological age=8.22), group 2 was composed of 18 children with BIF (chronological age=9.32), and group 3 was composed of 18 children with typical development (TD) (chronological age=9.28). Gr…

Impacto de la crisis en las entidades de acción social. Asindown, un ejemplo de superación

2013

La situación económica actual obliga a organismos públicos y empresas a adoptar medidas extraordinarias con el objetivo de mantener los servicios que prestan. En este contexto, las entidades (Fundaciones y Asociaciones) que atienden a personas con discapacidad y otros colectivos en riesgo de exclusión social, y que dependen en gran medida de las subvenciones públicas y privadas, sufren graves problemas de financiación que dificultan el normal desarrollo de sus actividades, y en consecuencia, son perjudicados aquellos usuarios y familias con las que trabajan. Asindown es parte de esta realidad y trabaja desde todos los ámbitos para mantener los servicios que presta con los mayores estándares…

REFERENTIAL COMUNICATION SKILL IN CHILDREN WITH DOWN SYNDROME

2014

OBJECTIVES: The aim of this study is to investigate the Referential Communication skill in children with Down Syndrome (DS). In particular in this research, we have studied the development of pragmatic language in relation to non-verbal skills. It’s analyzed the Referential Communication skills in children with DS, both in production and comprehension of referential messages: oriented and / or ambiguous , adequate (appropriate) and inadequate (inappropriate) METHODS: The participants in this research are a total of 24 children: 12 children with DS and 12 children with typical development (TD) (control group). The mean age children with DS is 7 years and 8 months and the mean age children wi…

Study of postural control and body balance in subjects with Down syndrome

2020

Purpose. Body imbalance and poor postural control have negative impact on gait and may increase the risk of falling in healthy individuals as well as those with Down syndrome (DS). Since people with DS have lower physical levels than people who do not present this condition, the purpose of our research was to compare features of postural control and body balance between subjects affected by DS and a control sample. Methods. Participants enrolled were divided into the following two groups: A DS group (DSG; n = 22; 9 females and 13 males; age range: 16-36 years) and an age-matched control group (CG; n = 25; 11 females and 14 males; age range: 16-36 years). All participants were subjected to t…

Improvement of gross motor and cognitive abilities by an exercise training program: three case reports

2014

Marianna Alesi,1 Giuseppe Battaglia,2 Michele Roccella,1 Davide Testa,1 Antonio Palma,2 Annamaria Pepi1 1Department of Psychology, 2Department of Law, Social and Sport Science, University of Palermo, Palermo, Italy Background: This work examined the efficacy of an integrated exercise training program (coach and family) in three children with Down syndrome to improve their motor and cognitive abilities, in particular reaction time and working memory. Methods: The integrated exercise training program was used in three children with Down syndrome, comprising two boys (M1, with a chronological age of 10.3 years and a mental age of 4.7 years; M2, with a chronological age of 14.6 years and a ment…

Gross-Motor and Cognitive Abilities in Down Syndrome: The efficacy of an integrated Exercised Training

2014

Motor Coordination and Global Development in Subjects with Down Syndrome: The Influence of Physical Activity

2022

Background: Many research studies have investigated motor impairments and delayed development in children with Down Syndrome (DS). However, very few studies detected these features in adults with DS. Hence, this study aimed to investigate the relationship between motor coordination and global development in subjects with DS, including adults. Furthermore, the second aim was to detect any differences in motor coordination and global development as a function of the practice of physical activity (PA) in this population. Methods: Twenty-five participants with DS (10 f, 15 m), with a chronological mean age of 27.24 years and development mean age of cognitive area of 4.93 years, were enrolled an…